The cell assembly hypothesis postulates that information processing in the brain entails the repetitive co-activation of groups of neurons . The activation of such assemblies would lead to spatio-temporal spike patterns (STPs) at the resolution of a few milliseconds. In order to test the cell assembly hypothesis, we searched for significant STPs in parallel spike trains, using the SPADE method [2,3]. We analyzed experimental data from the motor cortex (M1/PMd) of macaque monkeys (Macaca mulatta) performing a reach-to-grasp task  and found an abundance of STPs. Quantitative analysis showed that STPs are functionally related to behavior, which suggests the presence of assemblies activated during the task.
 Hebb, D. O. (1949). John Wiley & Sons
 Stella et al. (2019). Biosystems, 185, 104022. [doi: 10.1016/j.biosystems.2019.104022]
 Stella et al. (2022). eNeuro [doi: 10.1523/ENEURO.0505-21.2022]
 Brochier et al. (2018). Scientific data 5.1: 1-23. [doi: 10.12751/g-node.f83565]
Note: This is one of two talks in this seminar. The other talk is by Aitor Morales-Gregorio.
To obtain the Zoom link email firstname.lastname@example.org. Also indicate if you would like to be added to the mailing list for the Redwood Seminars.